SidaGhanaV1, Main, Exploration, bibRecord, 001006

Serological findings amongst first‐time blood donors in Yaoundé, Cameroon: is safe donation a reality or a myth?

Identifieur interne : 001006 ( Main/Exploration ); précédent : 001005; suivant : 001007

Serological findings amongst first‐time blood donors in Yaoundé, Cameroon: is safe donation a reality or a myth?

Auteurs : D. N. Mbanya [Cameroun] ; D. Takam ; P. M. Ndumbe [Cameroun]

Source :

Transfusion Medicine [ 0958-7578 ] ; 2003-10.

RBID : ISTEX:6BEF51A49E06AADF6EB2374E3875073A5257688F

Descripteurs français

Wicri :
- geographic : Cameroun, Tanzanie.
- topic : Transfusion sanguine, Don, Santé publique.

English descriptors

Abstract

Summary. Blood safety remains an issue of major concern in transfusion medicine in developing countries where national blood transfusion services and policies, appropriate infrastructure, trained personnel and financial resources are lacking. This is aggravated by the predominance of family and replacement, rather than regular benevolent, nonremunerated donors. Thus, in order to identify and encourage healthy, regular and benevolent nonremunerated donors, consenting first‐time blood donors in the Yaoundé University Teaching Hospital were screened for human immunodeficiency virus (HIV), hepatitis B surface antigen (HBSAg), hepatitis C virus (HCV), human T‐cell lymphotropic virus‐I (HTLV‐I) and syphilis using standard methods. Of 252 first‐time donors recruited, 66 (26·2%) were positive for at least one of the infections screened. There were 7·9% positive for HIV, 10·7% for HBSAg, 4·8% for HCV and 9·1 and 1·6%, respectively, for syphilis and HTLV‐I. About 30% of the 66 infected persons had co‐infections. HIV‐positive donors had a significantly increased risk of being positive for antibodies to syphilis (OR = 7·27; 95% CI = 2·23–23·51; P = 0·0007), not observed for HBV, HCV and HTLV‐I. These results suggest that blood transfusion is still very unsafe in this community and that it is imperative that emphasis be laid on donor education. Furthermore, donors with a history of sexually transmitted infections should be totally excluded from all donations.

Url:

https://api.istex.fr/document/6BEF51A49E06AADF6EB2374E3875073A5257688F/fulltext/pdf

DOI: 10.1046/j.1365-3148.2003.00453.x

Affiliations:

Cameroun

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Le document en format XML

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<term>Hepatitis</term>
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<term>High prevalences</term>
<term>High sensitivity</term>
<term>Human immunodeficiency virus</term>
<term>Human lymphotropic</term>
<term>Immunochromatographic assay</term>
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<term>Positive samples</term>
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<front><div type="abstract">Summary.  Blood safety remains an issue of major concern in transfusion medicine in developing countries where national blood transfusion services and policies, appropriate infrastructure, trained personnel and financial resources are lacking. This is aggravated by the predominance of family and replacement, rather than regular benevolent, nonremunerated donors. Thus, in order to identify and encourage healthy, regular and benevolent nonremunerated donors, consenting first‐time blood donors in the Yaoundé University Teaching Hospital were screened for human immunodeficiency virus (HIV), hepatitis B surface antigen (HBSAg), hepatitis C virus (HCV), human T‐cell lymphotropic virus‐I (HTLV‐I) and syphilis using standard methods. Of 252 first‐time donors recruited, 66 (26·2%) were positive for at least one of the infections screened. There were 7·9% positive for HIV, 10·7% for HBSAg, 4·8% for HCV and 9·1 and 1·6%, respectively, for syphilis and HTLV‐I. About 30% of the 66 infected persons had co‐infections. HIV‐positive donors had a significantly increased risk of being positive for antibodies to syphilis (OR = 7·27; 95% CI = 2·23–23·51; P = 0·0007), not observed for HBV, HCV and HTLV‐I. These results suggest that blood transfusion is still very unsafe in this community and that it is imperative that emphasis be laid on donor education. Furthermore, donors with a history of sexually transmitted infections should be totally excluded from all donations.</div>
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Serological findings amongst first‐time blood donors in Yaoundé, Cameroon: is safe donation a reality or a myth?

Serological findings amongst first‐time blood donors in Yaoundé, Cameroon: is safe donation a reality or a myth?

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri